Inflammation, Pain, and Alzheimer's Disease: Condition-based care

July 1 2003 David Seaman
Inflammation, Pain, and Alzheimer's Disease: Condition-based care
July 1 2003 David Seaman

A lzheimer's is a devastating disease that we should try to prevent, not only for ourselves, but also for our families. Patients with Alzheimer's disease lose cogni­tive function, emotional expression and memory, which essen­tially prevents them from experiencing the spice of life. It is no surprise to read that most patients enter a chiropractor's office looking for relief from various conditions, the most com- mon among them being back pain, neck pain, and > headache. During the history taking pro- cess, we typically dis- cover that such patients derive some relief from taking ibuprofen or similar anti-inflammatory drugs. which act to inhibit the syn­thesis of pro-inflammatory eicosanoids, such as prostag-landin E2 and thromboxane A2. Such inhibition results in less acti­vation of nociceptors and, therefore, less pain. Before 1990, researchers knew that anti-inflammatory drugs could prevent Alzheimer's disease. McGreer' stated that, "im-munohistochemical evidence points to a chronic inflammatory state of the brain in Alzheimer's disease, and data suggests that the prevalence of Alzheimer's in patients with rheumatoid ar­thritis is unexpectedly low and that anti-inflammatory therapy might be the explanation." This relationship between anti-in­flammatory drugs and Alzheimer's is now well established and has led researchers to search for natural alternatives that do not possess the serious side effects so common with long term use of drugs like ibuprofen. As it turns out, the prevalence of Alzheimer's in elderly folks in India over the age of eighty is only 4%, compared to 15.7% here in the states.2 Frautschy, el al., from UCLA, suggest that the liberal intake of turmeric may be the reason for this signifi­cant difference in Alzheimer's prevalence.2 It was determined that turmeric is both a potent antioxidant and anti-inflammatory agent that is capable of inhibiting prostaglandin E2 and other pro-inflammatory substances.2 Bucci explains that turmeric is effective in reducing musculoskelelal aches and pains, and can even be as effective as anti-inflammatory drugs.' 1 spoke with Frautschy, and she explained that ginger may be even more potent than turmeric. Ginger has also proven itself to be effective in reducing the pains associated with muscle injury, os-teoarthritis and rheumatoid arthri­tis thought to be a result of inhibi­tion of pro-inflammatory eicosanoid synthesis.4 Prostaglandin E2 causes pain and promotes Alzheimer's disease. Supplements such ginger and tur­meric can help our patients with aches and pains, and provide a nu­tritional adjustment. When taken long term, such supplements may be able to prevent dreaded chronic inflammatory conditions such as Alzheimer's disease. I, personally, drink homemade ginger tea, add powdered ginger to my meals and, when I am not doing either of these, I take ginger supplements. I suggest that you and your patients do the same. More on Alzheimer's in the next issue of TAC. Stay on the lookout. EZX3 See page 59 for References '■■'■';' Dr. Seaman is the Clinical Chiropractic Consultant for Anabolic Labo­ratories, one of the first supplement manufacturers to service the chiro­practic profession. He is on the faculty of Palmer College of Chiropractic Florida and on the postgraduate faculties of several other chiropractic colleges, providing nutrition seminars that focus on the needs of the chiropractic patient. Dr. Seaman believes that chiropractors should be thinking like chiropractors, while providing nutritional recommenda­tions. Doctors and patients who follow his programs report improved feelings of well-being, weight loss, dramatic increases in energy, and significant pain reduction. Dr. Seaman can he reached by e-mail at dacCiiJesspuiitbetlcrjiolt.com.